A microbiome researcher thinks Ozempic lifts mood by getting your gut bacteria to make cannabis-like compounds (psychologytoday.com)
A microbiome writer lays out a mechanism for why GLP-1 drugs lift mood: they grow a gut bacterium that makes cannabis-like endocannabinoids. In mice, removing the microbes erased the effect; a fecal transplant restored it.
Then the humans answered. One reports the opposite — anhedonia, a known side effect. Another lost insurance and now pays $450 a month, the returning weight 'making me more depressed.' Mice, as one reply noted, are not people.
Sign in to save